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brain health
Accelerating our understanding of neurological disease and pioneering new therapeutic strategies to benefit human health.
brain health team

One in three people are affected by neurological conditions. We’re finding new ways to treat them at the cellular level. 

We need to dramatically speed up our understanding of how the human brain works, both in health and disease, so we can accelerate progress toward new treatments.

Thanks to major breakthroughs in how we study the brain at the cellular and circuit level, powerful advances in AI, and our global network of collaborators, we finally have the tools – and the scale – to deeply understand the human brain and target cells affected by disease.

The Brain Health accelerator will focus initially on Alzheimer’s, Parkinson’s, Huntington’s, ALS and Lewy body dementia. Our large-scale, highly collaborative, open science approach aims to develop more treatment options for patients faster.

Brain Health is launching with a commitment to-date of $400M. This includes $200M from the Allen Institute, whose primary supporter is the Fund for Science and Technology; $100M from the Bezos family; and an additional $100M from AWS, NIH, and EverythingALS.

brain health news

news
Brain Health accelerator to transform our understanding of brain disorders and develop new treatments
the global collaborative research initiative will initially target Alzheimer’s, Parkinson’s, Huntington’s disease, ALS, and Lewy body dementia
video
Brain Health accelerator: a new way to study brain disease to find new treatments for it
understanding is hope—a new global research initiative to understanding the cells and circuits that drive brain disease so researchers can find new ways to rescue them.
news
collaboration expands research tool to help crack the code on Parkinson’s and other neurodegenerative diseases
a new view of Parkinson's Disease
The human brain is unlike anything else in biology. By working in human tissue at a scale that's never been attempted before, we're finally able to see disease at the cellular level and change everything about how we treat it.
Ed Lein
Executive Vice President and Director, Brain Health
We have new tools and technology to understand and treat brain disease. Massive advances in AI, and groundbreaking tools to develop targeted therapies are opening up a whole new chapter of human neuroscience and medicine.
Ed Lein
Executive Vice President and Director, Brain Health

featured publications

view all publications
publication / 2025
AAV delivery of full-length SYNGAP1 rescues epileptic and behavioral phenotypes in a mouse model of SYNGAP1-related disorders
Molecular Therapy: The Journal of the American Society of Gene Therapy
publication / 2025
Interneuron-specific dual-AAV SCN1A gene replacement corrects epileptic phenotypes in mouse models of Dravet syndrome
Science Translational Medicine
publication / 2024
SEA-AD is a multimodal cellular atlas and resource for Alzheimer's disease
Nature Aging
view all publications
Healthcare worker wearing blue scrubs and protective face shield examining patient with colleague nearby.

open access brain atlases, tools, and data and knowledge resources

science resources

brain health events

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brain health leadership

Anton Arkhipov
Investigator, D3 Scientific
Jeff Carroll
Investigator
Tanya L. Daigle
Investigator, Associate
Luke Esposito
Executive Director, Scientific Operations
Mariano Gabitto
Investigator, Assistant
Rebecca Hodge
Investigator, Associate
Nelson Johansen
Scientist II
Brian Kalmbach
Investigator, Assistant
Ed Lein
Executive Vice President and Director, Brain Health
Boaz P. Levi
Associate Investigator
Jonathan Ting
Investigator, Associate
Kyle Travaglini
Scientist II

brain health team

Emmie Banks
Scientist I - Alzheimer's Disease
Ananya Chowdhury
Scientist II
Kael Dai
SW Engineer III
Song-Lin Ding
Principal Scientist
Yi Ding
Bioinformatics Analyst III
Michal Fortuna
Scientist II, NHP Biodistribution Lead
Alex Fraser
Research Associate II
Yuanyuan Fu
Scientist 1
Aaron Garcia
Scientist I
Bryan Gore
Senior Scientist
Rong Guo
Scientist III
Rachel Hostetler
Scientist I
Shinya Ito
Scientist III
Inkar Kapen
Bioinformatics Analyst I
Hsin-Yu (Jane) Lai
Scientist I - ML/AI algorithms for Alzheimer's Disease
Will Laird
Research Associate I
Nathaly Lerma
Research Associate II
Jiatai (Augustus) Liu
Research Associate II
Xiao-Ping Liu
Scientist II
JT Mahoney
Research Associate III
John Mich
Senior Scientist
Jeremy Miller
Scientist, Sr.
Ximena Opitz-Araya
Research Associate, Principal
Nicholas Peña
Research Associate II
Meagan Quinlan
Scientist II
Matthew Schmitz
Scientist I
Nadiya Shapovalova
Research Associate Sr. Supervisor
Irika Sinha
Scientist I
Saroja Somasundaram
Bioinformatics Analyst II
Naz Taskin
Research Associate, Principal
Morgan Wirthlin
Scientist II

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Mapping every cell, connection, and circuit in the brain—openly shared with the world.

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Decoding how cells become tissues, then programming that knowledge into powerful new research tools.

neural dynamics

Revealing the brain's hidden algorithms that transform neural activity into real-world behavior.

immunology

Creating the deepest open reference for the healthy human immune system ever built.

synthetic biology

Engineering cells to record their own histories, transforming how we understand disease over time.

Brain Health

accelerating human brain research and new therapeutic strategies for neurological conditions

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Big questions, open answers, and science built to be shared.

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Inspiring the next generation of scientists through open science resources.

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