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Rebecca Hodge

Investigator, Assistant

teams /
Allenite

Rebecca Hodge is an Investigator, Assistant at the Allen Institute, working on large-scale projects to generate comprehensive, brain wide atlases of cellular diversity in human and non-human primate brains using multiomic and spatial transcriptomic methods. She is also a member of the Seattle Alzheimer’s Disease Cell Atlas consortium (SEA-AD) where she helps to lead efforts to generate a high-resolution multimodal cellular atlas of Alzheimer’s Disease. Prior to joining the Allen Institute, she completed her postdoctoral research at the University of Washington and the Center for Integrative Brain Research at Seattle Children’s Research Institute where she studied the actions of transcription factors during neurogenesis (the generation of neurons) in both the developing and adult brain. She completed her undergraduate training at Simon Fraser University and her graduate training was conducted at the University of British Columbia (UBC) in Vancouver, Canada.

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featured stories

news
A day in the (neuroscience) life: Human cell types
Scientists in this laboratory are exploring the molecular details of human - and other primate - brain cells
news
Highest-Resolution Human Brain 'Parts List' To Date Lays Road Map to Better Treatments for Neurological and Psychiatric Disorders
Crucial differences discovered in human and mice brain cells could explain why many drugs that work in the lab don’t work in us

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featured publications

publication / 2025
What makes the human brain special: from cellular function to clinical translation
Journal of Neurophysiology
publication / 2025
Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque
Cell Reports
publication / 2025
Integrating multimodal data to understand cortical circuit architecture and function
Nature Neuroscience
publication / 2023
Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus
Science Advances
publication / 2023
Transcriptomic diversity of cell types across the adult human brain
Science (New York, N.Y.)
publication / 2023
Single-cell DNA methylation and 3D genome architecture in the human brain
Science (New York, N.Y.)
publication / 2023
Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex
Science (New York, N.Y.)
publication / 2023
Comparative single-cell transcriptomic analysis of primate brains highlights human-specific regulatory evolution
Nature Ecology & Evolution
publication / 2022
Multi-modal characterization and simulation of human epileptic circuitry
Cell Reports
publication / 2022
Scalable in situ single-cell profiling by electrophoretic capture of mRNA using EEL FISH
Nature Biotechnology
publication / 2021
A multimodal cell census and atlas of the mammalian primary motor cortex
Nature
publication / 2021
A machine learning method for the discovery of minimum marker gene combinations for cell type identification from single-cell RNA sequencing
Genome Research
publication / 2021
Single-cell and single-nucleus RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates, and humans
eLife
publication / 2020
A community-based transcriptomics classification and nomenclature of neocortical cell types
Nature Neuroscience
publication / 2017
Cell type discovery and representation in the era of high-content single cell phenotyping
BMC bioinformatics
publication / 2017
STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array
Scientific Reports
publication / 2017
PRODUCTION OF A PRELIMINARY QUALITY CONTROL PIPELINE FOR SINGLE NUCLEI RNA-SEQ AND ITS APPLICATION IN THE ANALYSIS OF CELL TYPE DIVERSITY OF POST-MORTEM HUMAN BRAIN NEOCORTEX
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
publication / 2016
Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons
Nature Protocols
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