Associate Director, Molecular Biology
With 20 years’ experience overseeing large scale genomic and transcriptomic projects, Kim Smith has spent the last 14 of them at the Allen Institute influencing, producing, and managing many of the most well known Brain-map products. In particular, she has managed production groups, methods development, and data handling for six research atlases including the signature brain atlas and mouse spinal cord atlas. Kim currently serves as the manager of the Single Cell RNASeq Core, supporting the Cell Types Mouse and Human Projects.
Kim’s first experiences with large scale genomics project management was working on Chromosome 7 of the Human Genome Project, the Pseudomonas Genome Project, and the Rice Genome Project, all while at the University of Washington. She then went on to develop and manage the Center for Expression Arrays at the University of Washington, branching out into the new Microarray technology at the time. After a few years at a new biotechnology venture that did not succeed, Kim welcomed the opportunity to start at the ground floor of the Allen Institute for Brain Science, employing her experience both at the bench and at establishing new production pipelines.
Kim received a B.S. in Cell and Molecular Biology from the University of Washington.
As the first bench scientist hired at Allen Institute for Brain Science, Kim has enjoyed being a part of the growth and development of the Institute over the last 14 years. She is passionate about generating high quality datasets that have high impact on scientific understanding of our world. She enjoys developing new processes and production pipelines as the backbone to generating these datasets.
- Large scale, high throughput, genomic and transcriptomic projects
- Allen Brain Atlas
- Allen Human Brain Atlas
- Allen Developing Mouse Brain Atlas
- BrainSpan Atlas of the Developing Human Brain
- Non-Human Primate Atlas
- Human Brain and BrainSpan LCM & Microarray projects
- Ivy GAP (Glioblastoma)
- TBI RNASeq Project
- Allen Cell Types Database
February 19, 2019
Mich JK, Hess EE, Graybuck LT, Somasundaram S, Miller JA, Ding Y, Shapovalova NV, Fong O, Yao S, Mortrud M, Chong P, Bertagnolli D, Goldy J, Casper T, Kroll M, Hodge RD, Bakken TE, Yao Z, Dee N, Cetin A, Smith KA, Gwinn RP, Cobbs C, Ko AL, Ojemann JG, Keene CD, Silbergeld DL, Gradinaru V, Sunkin SM, Zeng H, Lein ES, Tasic B, Ting JT, Levi BP
August 27, 2018
Boldog E, Bakken TE, Hodge RD, Novotny M, Aevermann BD, Baka J, Bordé S, Jennie L. Close, Diez-Fuertes F, Ding SL, Faragó N, Kocsis AK, Kovács B, Maltzer Z, McCorrison JM, Miller JA, Molnár G, Oláh G, Ozsvár A, Rózsa M, Shehata SI, Smith KA, Sunkin SM, Tran DN, Venepally P, Wall A, Puskás LG, Barzó P, Steemers FJ, Schork NJ, Scheuermann RH, Lasken RS, Lein ES, Tamás G
July 12, 2018
Daigle TL, Madisen L, Hage TA, Valley MT, Knoblich U, Larsen RS, Takeno MM, Huang L, Gu H, Larsen R, Mills M, Bosma-Moody A, Siverts LA, Walker M, Graybuck LT, Yao Z, Fong O, Nguyen TN, Garren E, Lenz GH, Chavarha M, Pendergraft J, Harrington J, Hirokawa KE, Harris JA, Nicovich PR, McGraw MJ, Ollerenshaw DR, Smith KA, Baker CA, Ting JT, Sunkin SM, Lecoq J, Lin MZ2, Boyden ES, Murphy GJ, da Costa NM, Waters J, Li L, Tasic B, Zeng H
May 11, 2018
Puchalski RB, Shah N, Miller J, Dalley R, Nomura SR, Yoon JG, Smith KA, Lankerovich M, Bertagnolli D, Bickley K, Boe AF, Brouner K, Butler S, Caldejon S, Chapin M, Datta S, Dee N, Desta T, Dolbeare T, Dotson N, Ebbert A, Feng D, Feng X, Fisher M, Gee G, Goldy J, Gourley L, Gregor BW, Gu G, Hejazinia N, Hohmann J, Hothi P, Howard R, Joines K, Kriedberg A, Kuan L, Lau C, Lee F, Lee H, Lemon T, Long F, Mastan N, Mott E, Murthy C, Ngo K, Olson E, Reding M, Riley Z, Rosen D, Sandman D, Shapovalova N, Slaughterbeck CR, Sodt A, Stockdale G, Szafer A, Wakeman W, Wohnoutka PE, White SJ, Marsh D, Rostomily RC, Ng L, Dang C, Jones A, Keogh B, Gittleman HR, Barnholtz-Sloan JS, Cimino PJ, Uppin MS, Keene CD, Farrokhi FR, Lathia JD, Berens ME, Iavarone A, Amy Bernard A, Lein E, Phillips JW, Rostad SW, Cobbs C, Hawrylycz MJ, Foltz GD
December 26, 2018
Bakken TE, Hodge RD, Miller JA, Yao Z, Nguyen TN, Aevermann B, Barkan E, Bertagnolli D, Casper T, Dee N, Garren E, Goldy J, Graybuck LT, Kroll M, Lasken RS, Lathia K, Parry S, Rimorin C, Scheuermann RH, Schork NJ, Shehata SI, Tieu M, Phillips JW, Bernard A, Smith KA, Zeng H, Lein ES, Tasic B
October 31, 2018
Tasic B, Yao Z, Graybuck LT, Smith KA, Nguyen TN, Bertagnolli D, Goldy J, Garren E, Economo MN, Viswanathan S, Penn O, Bakken T, Menon V, Miller J, Fong O, Hirokawa KE, Lathia K, Rimorin C, Tieu M, Larsen R, Casper T, Barkan E, Kroll M, Parry S, Shapovalova NV, Hirschstein D, Pendergraft J, Sullivan HA, Kim TK, Szafer A, Dee N, Groblewski P, Wickersham I, Cetin A, Harris JA, Levi BP, Sunkin SM, Madisen L, Daigle TL, Looger L, Bernard A, Phillips J, Lein E, Hawrylycz M, Svoboda K, Jones AR, Koch C, Zeng H
October 31, 2018
Economo MN, Viswanathan S, Tasic B, Bas E, Winnubst J, Menon V, Graybuck LT, Nguyen TN, Smith KA, Yao Z, Wang L, Gerfen CR, Chandrashekar J, Zeng H, Looger LL, Svoboda K
As Senior Manager of Molecular Biology at Allen Institute, Kim leads three production teams. The Histology team is responsible for production tissue staining, ISH, and reagent preparation. The Genotyping team is responsible for providing end point genotyping results in support of our Transgenic Colony Management team. The Single Cell RNASeq Core, the largest of the teams, is responsible for all single cell and nucleus RNA Sequencing.